Downstream Process Development Associate

Job Description

Location:: Pearl River, New York

Visa Status:: Any work visa (Visa sponsorship available)

Salary::$130k P.A.

Duration::

Job Description:

Job Overview

As an Downstream Process Development Associate, the incumbent will report directly to the Head of Process Development and will be responsible for the day to day design and execution of laboratory experiments to develop scalable downstream processes for the purification of recombinant protein or viral vectors.

 Responsibilities 

·        Design and execute laboratory experiments to develop scalable downstream process for the purification of recombinant protein or viral vectors

·        Knowledge in recombinant protein or viral vector purification processes, including chromatography process (i.e. IEX, affinity, SEC, reversed-phase), ultrafiltration / diafiltration, process scale up, scale down model qualification, viral and depth filtration

·        Ability to optimize processes for product purity, recovery, impurity removal, and cost reduction

·        Assist in tech transfer of small-scale process to contract manufacturing organization (CMO) for scale-up

·        Assists with preparing protocols, reports, and test methods

·        Ability to foster a collaborative work environment with internal and external partners

 

Skills & Requirements-

·        Good foundation in general scientific practice, principles, and concepts of discipline.

·        Basic knowledge of GMP/GLP regulations in cGMP/cGLP manufacturing environment preferred.

·        Good lab skills.

·        Good problem-solving and critical thinking skills.

·        Effective communication skills.

·        Good MS Excel and Word skills.

·        Excellent organization skills.

·        Ability to execute tasks and studies based on the deliverable timeline.

·        Ability to analyze and summarize routine scientific data.

·        Ability to function in a rapidly changing environment.

 

Education & Experience

• Ph.D. in Biotechnology, Protein Chemistry, Biochemistry or Chemical/Biochemical Engineering with minimal 2 + years or MS with minimal 6+ years of relevant industrial experience

Qualification::